What is Rabies? Symptoms and treatment
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In rabies, there is inflammation of the brain, encephalitis. The rabies virus enters the central nervous and peripheral nervous system and starts producing infection in the brain and spine.
Animal bites are the most common cause of rabies. Both domestic and wild animals are capable of transmitting the deadly rabies virus by biting humans. In general, most of the cases of rabies account for the bites by stray dogs.
The virus responsible for cauing rabies can cross the blood brain barrier very rapidly once it reaches our brain via blood stream. Once it reaches the brain, the survival chances decrease and the fatality rate increases. It can even cause death of the person, if not treated properly.
Pre-prophylaxis and postprohylaxis vaccines are proven to be useful in preventing the risk of infection or preventing the infection to spread inside the body and reach the brain.
Can a dog bite cause Rabies?
Yes. Animal bites are the common cause of Rabies. The infected animals carry rabies virus in their saliva and when they bite a human, they can transfer the virus to the person. The wound caused by the bite makes it easy for the virus to enter the blood and body cells. Sharp scratches from animal nails can also infect humans.
Stray dogs are the reservoir of RABV rabies virus as they are unvaccinated. Unvaccinated pets can also be infected if it gets bitten by the infected stray dogs.
Which animals can cause rabies in humans?
- Mostly stray dogs are the cause but depending upon your geographical biodiversity it can be an animal most commonly seen in your location.
- Stray dogs and cats are common in developing countries.
- Both domestic and wild animals are affected by the virus and when they bite, it can cause rabies in humans or other animals.
- Animals such as bats, coyotes, skunks, foxes, raccons, rabbits, goats, horses, etc be infected with the rabies virus and infect humans and other animals by their bite.
Who are at risk of contracting the rabies virus infection?
- Children upto 15 years are at more risk of contracting rabies via animal bite.
- People who reside in a locality where there are multiple bats. In the US, bats are the common cause of rabies.
- People living in developing countries where there are more domestic stray dogs and cats.
- People who travel to developing countries without getting preprophylatic vaccines for rabies.
- People who keep unvaccinated pets at home.
- People who are zookeeper or work in animal welfare centers
- People who look after infected animals.
- People who often go to wild life camping.
What are the signs and symptoms seen in Rabies?
Fever is the most common and initial symptoms seen in Rabies. A person may feel sick like having flu. The infection spreads very slowly as the virus may take 1-3 months to show the symptoms, once you get a bite.
It may take many months to a year for the rabies virus to reach the brain through the peripheral nervous system. The neurological symptoms start to appear as the virus causes infection in the brain. Once the neurological symptoms start, it becomes quite impossible to manage the situation or save life. The fatality increases at this point. The treatment may not be successful at this stage of infection into your brain.
Following are the signs and symptoms of rabies:
- Fever with chills
- Malaise
- Muscle aches and fatigue
- Nausea and vomiting
- Diarrhea
- Headache
- Burning at the site of bite
- Tingling and numbness at the site of bite(wound)
- Furious rabies
- Paralytic rabies
What are the symptoms of furious rabies?
- Fever
- Irritability
- Agitation
- Confusion and hallucination
- Anxiety and insomnia
- Excess saliva production and drooling of saliva
- Fear of water(hydrophobia)
- Fear of swallowing water
- The mere sight of water or liquids may stimulate a fear response.
- Fear of air blown on the face (aerophobia)
- Increased heart rate or tachycardia
- Rapid breathing
- Severe muscle twitching or contractions
- Seizure attacks
- Delirium stage
- Facial paralysis
- Fever continues
- Stiffness of the neck
- Paralysis of the body
- Coma
How do we know it is rabies? How to diagnose rabies?
Your doctor may need to ask a series of question to you:
- When did you get animal bite?
- Was it a pet or some stray animal?
- Was it a wild animal?
- Do you know the animal that bite you/are you familiar about its owner?
- Was the animal in agitated state when it bite you?
- Do you know about the vaccination status if it was a pet animal?
- Are you prevaccinated ever with rabies vaccine?
- Can you find that animal and check its health status over a month?
- Saliva test for virus detection
- Lumbar puncture test to aspirate CSF to detect virus in the cerebrospinal fluid
- CT scan and MRI to know the changes in the brain and spine
- Blood culture tests
What is the treatment of rabies?
- 4 Post prophylaxis vaccine shots are given over 14 days
- Human immunoglobulin vaccine may be given at the site of the wound to kill the virus near or on the wound skin.
- If you are already pre-vaccinated before the bite, talk to the doctor. You may require just 2 shots of rabies vaccine then.
- Take care of the wound until it gets healed completely. Take antibiotics to prevent any wound infection other than rabies. Open wound tend to get infected by fungus and bacteria. Apply povidone iodine solution or antiseptic cream to your wound as ordered by your doctor.
- Follow up as ordered by your doctor.
Is rabies a preventable viral disease?
- Rabies can be prevented. Proper care of pets and keeping yourself and your pets vaccinated ensures the safety from rabies.
- Ensure all your pets get their vaccines for rabies
- You also get vaccinated for rabies on a regular basis, if you live in risk-prone areas.
- Whenever you visit wildlife or go camping in forest, stay away from the wild animals
- Never touch the injured wild animals.
- Always make sure your pets are with you or not going out without supervision.
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